RT Journal Article SR Electronic T1 Permeation of d5-2,4,6-Trichloroanisole via Vapor Phase through Different Closures into Wine Bottles JF American Journal of Enology and Viticulture JO Am. J. Enol. Vitic. FD American Society for Enology and Viticulture SP ajev.2010.10098 DO 10.5344/ajev.2010.10098 A1 Paulo Lopes A1 Juliana Marques A1 Tânia Lopes A1 José Lino A1 Joaquim Coelho A1 Cátia Alves A1 Isabel Roseira A1 Adélio Mendes A1 Miguel Cabral YR 2011 UL http://www.ajevonline.org/content/early/2011/02/23/ajev.2010.10098.abstract AB This study outlines the results from an experiment to find evidence of the sealing effectiveness of different closures towards the permeation of exogenous compounds when bottled wine model solutions were stored in a contaminated environment with deuterium-labeled 2,4,6-trichloroanisole (d5-TCA). Wine model solutions and closures fractions (outer, middle and inner) were assessed over time for the concentration of releasable d5-TCA by SPME-GC-MS. During the 24 months of storage, large amounts of d5-TCA were essentially retained in the outer portions of natural and microagglomerate corks. Under the conditions of this experiment, the natural and microagglomerate cork stoppers were effective barriers to the transmission of exogenous contaminants. Conversely, d5-TCA penetrated synthetic closures and contaminated the wine.