… L, platelet count ≥100 × 10 9 platelets per L, and haemoglobin ≥9 g/dL), hepatic function
(total bilirubin concentration ≤1·5 times the upper limit of normal and aspartate and alanine …

Histidine kinases allow bacteria, plants, and fungi to sense and respond to their environment.
The 2.6 Å resolution crystal structure of Thermotoga maritima CheA (290-671) histidine …

… While the precise mechanisms of action remain unclear, topiramate is thought to reduce
neuronal excitability through inhibition at glutamate AMPA/kainate receptors and L-type calcium …

… A chest X-ray was equally within normal limits without signs of lung metastases. Pelvic
Magnetic Resonance Imaging (MRI) revealed a mass with heterogeneous intensity and …

Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United
States have served as a visible and important communication channel between the scientific …

Objective: Pharmacological treatments that can concomitantly address cigarette smoking
and heavy drinking stand to improve health care delivery for these highly prevalent co-…

WE have used surface plasmon resonance biosensor technology to monitor the assembly
and dynamics of a signal transduction complex which controls chemotaxis in Escherichia coli …

Aims Alcohol use disorder is highly heterogeneous. One approach to understanding this
heterogeneity is the identification of drinker subtypes. A candidate classification consists of …

This crowdsourced project introduces a collaborative approach to improving the
reproducibility of scientific research, in which findings are replicated in qualified independent …

Despite a well-documented global burden of disease attributable to alcohol use disorder (AUD),
treatment seeking rates remain low. In this qualitative literature review, we address …