User profiles for Shuwen Liu
 | Shuwen LiuSouthern Medical University Verified email at smu.edu.cn Cited by 32119 |
[HTML][HTML] Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high …
S Xia, M Liu, C Wang, W Xu, Q Lan, S Feng, F Qi, L Bao… - Cell research, 2020 - nature.com
The recent outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 infection
in Wuhan, China has posed a serious threat to global public health. To develop specific anti-…
in Wuhan, China has posed a serious threat to global public health. To develop specific anti-…
[HTML][HTML] The spike protein of SARS-CoV—a target for vaccine and therapeutic development
L Du, Y He, Y Zhou, S Liu, BJ Zheng… - Nature Reviews …, 2009 - nature.com
Severe acute respiratory syndrome (SARS) is a newly emerging infectious disease caused
by a novel coronavirus, SARS-coronavirus (SARS-CoV). The SARS-CoV spike (S) protein is …
by a novel coronavirus, SARS-coronavirus (SARS-CoV). The SARS-CoV spike (S) protein is …
[HTML][HTML] Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
Similar to severe acute respiratory syndrome (SARS)-CoV, 2019-nCoV belongs to lineage
B betacoronavirus, and it has the ability to utilize human angiotensin-converting enzyme 2 (…
B betacoronavirus, and it has the ability to utilize human angiotensin-converting enzyme 2 (…
[HTML][HTML] Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and …
S Liu, G Xiao, Y Chen, Y He, J Niu, CR Escalante… - The Lancet, 2004 - thelancet.com
Background Studies on the fusion-inhibitory peptides derived from the heptad repeat 1 and
2 (HR1 and HR2) regions of the HIV-1 envelope glycoprotein gp41 provided crucial …
2 (HR1 and HR2) regions of the HIV-1 envelope glycoprotein gp41 provided crucial …
Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine
The spike (S) protein of severe acute respiratory syndrome (SARS) coronavirus (CoV), a
type I transmembrane envelope glycoprotein, consists of S1 and S2 domains responsible for …
type I transmembrane envelope glycoprotein, consists of S1 and S2 domains responsible for …
[HTML][HTML] Quercetin as an antiviral agent inhibits influenza A virus (IAV) entry
Influenza A viruses (IAVs) cause seasonal pandemics and epidemics with high morbidity
and mortality, which calls for effective anti-IAV agents. The glycoprotein hemagglutinin of …
and mortality, which calls for effective anti-IAV agents. The glycoprotein hemagglutinin of …
Archean geodynamics in the Central Zone, North China Craton: constraints from geochemistry of two contrasting series of granitoids in the Fuping and Wutai …
The Archean to Paleoproterozoic Central Zone of the North China Craton is situated between
the Eastern and Western Archean continental blocks and contains two contrasting series of …
the Eastern and Western Archean continental blocks and contains two contrasting series of …
Th–U–Pb monazite geochronology of the Lüliang and Wutai Complexes: constraints on the tectonothermal evolution of the Trans-North China Orogen
S Liu, G Zhao, SA Wilde, G Shu, M Sun, Q Li… - Precambrian …, 2006 - Elsevier
Recent lithological, metamorphic and geochronological studies show that the basement of
the North China Craton (NCC) formed by collision of two discrete Archean to …
the North China Craton (NCC) formed by collision of two discrete Archean to …
N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus …
A recently approved peptidic human immunodeficiency virus type 1 (HIV-1) fusion inhibitor,
T-20 (Fuzeon; Trimeris Inc.), has shown significant promise in clinical application for treating …
T-20 (Fuzeon; Trimeris Inc.), has shown significant promise in clinical application for treating …
Geological and isotopic geochemical constraints on the evolution of the Fuping Complex, North China Craton
The Neoarchean to Paleoproterozoic Fuping Complex together with the adjacent Hengshan
and Wutaishan complexes form the middle part of the Central Zone that separates the North …
and Wutaishan complexes form the middle part of the Central Zone that separates the North …