We present two new desorption strategies for the mass spectrometric analysis of macromolecules.
These desorption strategies are based on the molecular design and construction of …

The ability to define specific alterations in the structure and function of proteins as they are
introduced and processed in vivo remains an important goal. We have evaluated the …

Lactoferricin is a bioactive peptide fragment (3196 Da) derived from lactoferrin (80 kDa) that
contains the bactericidal domain and the lymphocyte receptor-binding domain of lactoferrin. …

ABSTRACT: The origin of intact (78-kD) lactoferrin found in the urine of human milk-fed
preterm infants was investigated using human milk containing proteins enriched with [13 C] …

… In fact evidence (RJ Shulman and TW Hutchens unpublished), based on the analysis, by …
(Hutchens & Yip, 1992). Once again preliminary results (RJ Shulman and TW Hutchens unpub …

Immunoglobulins have been selected by their general affinity for adjacent sulfone-thioether
sulfur groups as a useful model system for the characterization of thiophilic interaction …

A method of protein quantitative analysis using matrix-assisted laser desorption/ionization
time-of-flight mass spectrometry is described. To decouple the quantitative approach from the …

The human progesterone receptor (hPR) in T47D breast cancer cells is phosphorylated on
at least nine different serine residues. We have previously reported the identification of five …

Two forms of lactoferrin, an intact lactoferrin and a "nicked" but apparently intact (ie, 78-kDa)
form, have been isolated from the urine of preterm infants fed human milk. These two forms …

… and Hutchens, TW, unpublished work). Because the spectra obtained from the faeces of two
groups fed milk enriched with lactoferrin were very similar, only a representative spectrum is …