Surgery for small liver cancers

M Makuuchi, T Kosuge, T Takayama… - Seminars in surgical …, 1993 - Wiley Online Library
During the last 16 years, we have resected small hepatocellular carcinomas (HCCs) measuring
5 cm or less from 362 patients, 266 of whom also had liver cirrhosis. The operative and …

The role of phenolics in host response to infection

T Kosuge - Annual Review of Phytopathology, 1969 - annualreviews.org
… Carroll, TW, Kosuge, T. Changes in structure of chloroplasts accom panying necrosis of
tobacco leaves systematically infected with to bacco mosaic virus. Phytopathol ogy (In press) …

Improved surgical results for hilar cholangiocarcinoma with procedures including major hepatic resection

T Kosuge, J Yamamoto, K Shimada, S Yamasaki… - Annals of …, 1999 - journals.lww.com
Objective To evaluate the long-term outcome of aggressive surgery incorporating hepatic
resection and systematic nodal dissection for advanced carcinoma involving the hepatic hilus. …

Preoperative portal embolization to increase safety of major hepatectomy for hilar bile duct carcinoma: a preliminary report.

…, BL Thai, K Takayasu, T Takayama, T Kosuge… - Surgery, 1990 - europepmc.org
Extensive liver resection for hilar bile duct carcinoma with jaundice has high morbidity and
mortality rates because of postoperative liver failure. To minimize postoperative liver …

Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial

…, T Sekine, M Makuuchi, S Yamasaki, T Kosuge… - The Lancet, 2000 - thelancet.com
… We developed a 2-week culture system that ensures about 1000-fold T-cell expansion from
… , on receipt of the pathological confirmation of T category, no later than 1 week after surgery. …

[HTML][HTML] Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer

…, K Shimada, M Iwasaki, T Kosuge… - British journal of …, 2013 - nature.com
Background: The host immune reaction is represented by immune/inflammatory cell
infiltrates. Here we systematically analysed tumour-infiltrating immune/inflammatory cells in …

Genomic spectra of biliary tract cancer

…, T Okusaka, T Kosuge, S Miyagawa, T Shibata - Nature …, 2015 - nature.com
… C>T/G>A substitutions, followed by T>C/A>G and C>A/T>G substitutions, represented the
dominant somatic substitution pattern for BTCs (Supplementary Fig. 1b). The predominance of …

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

…, M Yamamoto, T Yamada, K Chayama, T Kosuge… - Nature …, 2012 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death
worldwide. We sequenced and analyzed the whole genomes of 27 HCCs, 25 of which were …

Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

…, T Okusaka, N Kokudo, T Kosuge, T Takayama… - Nature …, 2014 - nature.com
… If a variant was present in reads of only one orientation, we checked for strand bias using
a t test comparing these reads to the reads without the variant, and variants with a P value of <…

Extension of the frontiers of surgical indications in the treatment of liver metastases from colorectal cancer: long-term results

…, G Torzilli, T Takayama, S Kawasaki, T Kosuge… - Annals of …, 2000 - journals.lww.com
… Yasui K, Hirai T, Kato T, et al. A new macroscopic classification predicts prognosis for
patient with liver metastasis from colorectal cancer. Ann Surg 1997; 226:582–586 …