BACKGROUND Forest dynamics arise from the interplay of chronic drivers and transient
disturbances with the demographic processes of recruitment, growth, and mortality. The …

Soils are subject to varying degrees of direct or indirect human disturbance, constituting a
major global change driver. Factoring out natural from direct and indirect human influence is …

Recent observations of elevated tree mortality following climate extremes, like heat and drought,
raise concerns about climate change risks to global forest health. We currently lack both …

… a T on their 5′ side) that change the C to either T or G or (less often) A. This pattern is
characteristic of mutations caused by the APOBEC family of cytidine deaminases, innate immunity …

Mutations in mitochondrial DNA (mtDNA) accumulate in tissues of mammalian species and
have been hypothesized to contribute to aging. We show that mice expressing a proofreading…

Lung adenocarcinoma, the most common subtype of non-small cell lung cancer, is responsible
for more than 500,000 deaths per year worldwide. Here, we report exome and genome …

This is a development of the present authors' (with IPSEN) 1960 text, Epidemiologic Methods
[Bull. Hyg., 1961, v. 36, 957]. The influence of the earlier work is of course apparent, but the …

Multiple myeloma is an incurable malignancy of plasma cells, and its pathogenesis is poorly
understood. Here we report the massively parallel sequencing of 38 tumour genomes and …

Here we present the results from an intercomparison of multiple global gridded crop models
(GGCMs) within the framework of the Agricultural Model Intercomparison and Improvement …

Prostate cancer is the second most common cause of male cancer deaths in the United
States. However, the full range of prostate cancer genomic alterations is incompletely …