User profiles for A. Gavin

Anne-Claude Gavin

Switzerland
Verified email at unige.ch
Cited by 21802

[HTML][HTML] Cancer incidence and mortality patterns in Europe: Estimates for 40 countries and 25 major cancers in 2018

…, T Dyba, G Randi, M Bettio, A Gavin… - European journal of …, 2018 - Elsevier
Introduction Europe contains 9% of the world population but has a 25% share of the global
cancer burden. Up-to-date cancer statistics in Europe are key to cancer planning. Cancer …

Visualization of omics data for systems biology

…, H Neuweger, R Schneider, D Tenenbaum, AC Gavin - Nature …, 2010 - nature.com
High-throughput studies of biological systems are rapidly accumulating a wealth of 'omics'-scale
data. Visualization is a key aspect of both the analysis and understanding of these data, …

[HTML][HTML] Modules, networks and systems medicine for understanding disease and aiding diagnosis

…, S Brunak, KF Chung, HJ Federoff, AC Gavin… - Genome medicine, 2014 - Springer
Many common diseases, such as asthma, diabetes or obesity, involve altered interactions
between thousands of genes. High-throughput techniques (omics) allow identification of such …

Proteome survey reveals modularity of the yeast cell machinery

AC Gavin, P Aloy, P Grandi, R Krause, M Boesche… - Nature, 2006 - nature.com
Protein complexes are key molecular entities that integrate multiple gene products to
perform cellular functions. Here we report the first genome-wide screen for complexes in an …

Functional organization of the yeast proteome by systematic analysis of protein complexes

AC Gavin, M Bösche, R Krause, P Grandi, M Marzioch… - Nature, 2002 - nature.com
Most cellular processes are carried out by multiprotein complexes. The identification and
analysis of their components provides insight into how the ensemble of expressed proteins (…

Drug target identification using side-effect similarity

M Campillos, M Kuhn, AC Gavin, LJ Jensen, P Bork - Science, 2008 - science.org
Targets for drugs have so far been predicted on the basis of molecular or cellular features,
for example, by exploiting similarity in chemical structure or in activity across cell lines. We …

TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome

…, BE Krumm, ST Slocum, T Che, AC Gavin… - Nature chemical …, 2020 - nature.com
G-protein-coupled receptors (GPCRs) remain major drug targets, despite our incomplete
understanding of how they signal through 16 non-visual G-protein signal transducers (…

[HTML][HTML] The European cancer burden in 2020: Incidence and mortality estimates for 40 countries and 25 major cancers

…, C Martos, F Giusti, N Nicholson, A Gavin… - European Journal of …, 2021 - Elsevier
Introduction Europe is an important focus for compiling accurate and up-to-date world cancer
statistics owing to its large share of the world's total cancer burden. This article presents …

Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

AL Gavin, K Hoebe, B Duong, T Ota, C Martin… - Science, 2006 - science.org
Innate immune signals mediated by Toll-like receptors (TLRs) have been thought to contribute
considerably to the antibody-enhancing effects of vaccine adjuvants. However, we report …

[PDF][PDF] Use of complementary/alternative medicine by breast cancer survivors in Ontario: prevalence and perceptions

…, C Sawka, JB Brown, C McWilliam, A Gavin… - Journal of Clinical …, 2000 - Citeseer
Purpose: To determine the prevalence of use of complementary/alternative medicine (CAM)
by breast cancer survivors in Ontario, Canada, and to compare the characteristics of CAM …