Background Lignin, nature’s dominant aromatic polymer, is found in most terrestrial plants in
the approximate range of 15 to 40% dry weight and provides structural integrity. Traditionally…

Agricultural expansion and climate variability have become important agents of disturbance
in the Amazon basin. Recent studies have demonstrated considerable resilience of …

For cellulosic ethanol to become a reality, biotechnological solutions should focus on
optimizing the conversion of biomass to sugars.

Schizophrenia has a heritability of 60–80% 1 , much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …

BACKGROUND: The 16-item Quick Inventory of Depressive Symptomatology (QIDS), a new
measure of depressive symptom severity derived from the 30-item Inventory of Depressive …

ContextRisedronate, a potent bisphosphonate, has been shown to be effective in the treatment
of Paget disease of bone and other metabolic bone diseases but, to our knowledge, it …

The German manufacturing industry has to withstand an increasing global competition on
product quality and production costs. As labor costs are high, several industries have suffered …

NF‐κB is responsible for upregulating gene products that control cell survival. In this study,
we demonstrate that SIRT1, a nicotinamide adenosine dinucleotide‐dependent histone …

• In 1988, the MacArthur Foundation Research Network on the Psychobiology of Depression
convened a task force to examine the ways in which change points in the course of …

We conducted a meta-analysis of Parkinson's disease genome-wide association studies
using a common set of 7,893,274 variants across 13,708 cases and 95,282 controls. Twenty-six …