Donepezil hydrochloride (E2020) and other acetylcholinesterase inhibitors
…, Y Yamanish, Y Iimura, Y Kawakami - Current medicinal …, 2000 - ingentaconnect.com
A wide range of evidence shows that acetylcholinesterase (AChE) inhibitors can interfere
with the progression of Alzheimer disease (AD). The successful development of these …
with the progression of Alzheimer disease (AD). The successful development of these …
Research and development of donepezil hydrochloride, a new type of acetylcholinesterase inhibitor
…, H Ogura, Y Arai, Y Iimura, Y Yamanishi - The Japanese journal …, 2002 - jstage.jst.go.jp
A wide range of evidence shows that cholinesterase (ChE) inhibitors can interfere with the
progression of Alzheimer’s disease (AD). The earliest known ChE inhibitors, namely, …
progression of Alzheimer’s disease (AD). The earliest known ChE inhibitors, namely, …
SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells
R Hamamoto, Y Furukawa, M Morita, Y Iimura… - Nature cell …, 2004 - nature.com
Colorectal and hepatocellular carcinomas are some of the leading causes of cancer deaths
worldwide, but the mechanisms that underly these malignancies are not fully understood. …
worldwide, but the mechanisms that underly these malignancies are not fully understood. …
Synthesis and structure-activity relationships of acetylcholinesterase inhibitors: 1-benzyl-4-[(5, 6-dimethoxy-1-oxoindan-2-yl) methyl] piperidine hydrochloride and …
H Sugimoto, Y Iimura, Y Yamanishi… - Journal of medicinal …, 1995 - ACS Publications
Following the discovery of a new series of anti-acetylcholinesterase (anti-AChE) inhibitors
such as l-benzyl-4-[2-CZV-benzoylamino) ethyl] piperidine (1), we reported that its rigid …
such as l-benzyl-4-[2-CZV-benzoylamino) ethyl] piperidine (1), we reported that its rigid …
Integrative Transformation of Aspergillus oryzae with a Plasmid Containing the Aspergillus nidulans argB Gene
K Gomi, Y Iimura, S Hara - Agricultural and biological chemistry, 1987 - Taylor & Francis
The transformation of Aspergillus oryzae has been achieved with a plasmid carrying the
Aspergillus nidulans argB gene coding for ornithine carbamoyltransferase (OCTase). The …
Aspergillus nidulans argB gene coding for ornithine carbamoyltransferase (OCTase). The …
Incidence of benign pathologic lesions at partial nephrectomy for presumed RCC renal masses: Japanese dual-center experience with 176 consecutive patients
Y Fujii, Y Komai, K Saito, Y Iimura, J Yonese… - Urology, 2008 - Elsevier
OBJECTIVES: To determine the incidence of benign pathologic findings at elective partial
nephrectomy for renal masses thought to be renal cell carcinoma (RCC) on preoperative …
nephrectomy for renal masses thought to be renal cell carcinoma (RCC) on preoperative …
Selective isolation of bioactive soil actinomycetes belonging to the Streptomyces violaceusniger phenotypic cluster
M Hayakawa, Y Yoshida, Y Iimura - Journal of Applied …, 2004 - academic.oup.com
Aims: To devise and evaluate a strategy for isolating members of the Streptomyces violaceusniger
phenotypic cluster, which are known to be a promising source of bioactive metabolites…
phenotypic cluster, which are known to be a promising source of bioactive metabolites…
Raw-starch-digesting and thermostable α-amylase from the yeast Cryptococcus sp. S-2: purification, characterization, cloning and sequencing
H Iefuji, M Chino, M Kato, Y Iimura - Biochemical Journal, 1996 - portlandpress.com
A starch-degrading enzyme produced by the yeast Cryptococcus sp. S-2 was purified in only
one step by using an α-cyclodextrin–Sepharose 6B column, and was characterized as an α-…
one step by using an α-cyclodextrin–Sepharose 6B column, and was characterized as an α-…
Sed1p Is a Major Cell Wall Protein ofSaccharomyces cerevisiae in the Stationary Phase and Is Involved in Lytic Enzyme Resistance
H Shimoi, H Kitagaki, H Ohmori, Y Iimura… - Journal of …, 1998 - Am Soc Microbiol
A 260-kDa structural cell wall protein was purified from sodium dodecyl sulfate-treated cell
walls of Saccharomyces cerevisiae by incubation with Rarobacter faecitabidusprotease I, …
walls of Saccharomyces cerevisiae by incubation with Rarobacter faecitabidusprotease I, …
Molecular Cloning and Characterization of a Transcriptional Activator Gene, amyR, Involved in the Amylolytic Gene Expression in Aspergillus oryzae
…, C Kumagai, N Okazaki, Y Iimura - Bioscience …, 2000 - academic.oup.com
A gene, designated amyR, coding for a transcriptional activator involved in amylolytic gene
expression has been cloned from Aspergillus oryzae by screening for a clone that enabled to …
expression has been cloned from Aspergillus oryzae by screening for a clone that enabled to …