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Page 1
Substituted thiophene-anthranilamides as potent inhibitors of human factor Xa.
Bioorg Med Chem. 2007 Mar 1;15(5):2127-46. doi: 10.1016/j.bmc.2006.12.019. Epub 2006 Dec 13.
Bioorg Med Chem. 2007.
PMID: 17227710
Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain.
Dovey HF, John V, Anderson JP, Chen LZ, de Saint Andrieu P, Fang LY, Freedman SB, Folmer B, Goldbach E, Holsztynska EJ, Hu KL, Johnson-Wood KL, Kennedy SL, Kholodenko D, Knops JE, Latimer LH, Lee M, Liao Z, Lieberburg IM, Motter RN, Mutter LC, Nietz J, Quinn KP, Sacchi KL, Seubert PA, Shopp GM, Thorsett ED, Tung JS, Wu J, Yang S, Yin CT, Schenk DB, May PC, Altstiel LD, Bender MH, Boggs LN, Britton TC, Clemens JC, Czilli DL, Dieckman-McGinty DK, Droste JJ, Fuson KS, Gitter BD, Hyslop PA, Johnstone EM, Li WY, Little SP, Mabry TE, Miller FD, Audia JE.
Dovey HF, et al. Among authors: sacchi kl.
J Neurochem. 2001 Jan;76(1):173-81. doi: 10.1046/j.1471-4159.2001.00012.x.
J Neurochem. 2001.
PMID: 11145990
Free article.
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Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors.
Ye B, Arnaiz DO, Chou YL, Griedel BD, Karanjawala R, Lee W, Morrissey MM, Sacchi KL, Sakata ST, Shaw KJ, Wu SC, Zhao Z, Adler M, Cheeseman S, Dole WP, Ewing J, Fitch R, Lentz D, Liang A, Light D, Morser J, Post J, Rumennik G, Subramanyam B, Sullivan ME, Vergona R, Walters J, Wang YX, White KA, Whitlow M, Kochanny MJ.
Ye B, et al. Among authors: sacchi kl.
J Med Chem. 2007 Jun 28;50(13):2967-80. doi: 10.1021/jm070125f. Epub 2007 May 31.
J Med Chem. 2007.
PMID: 17536795
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Intramolecular palladium-catalyzed allylic alkylation: enantio- and diastereoselective synthesis of [2.2.2] bicycles.
Trost BM, Sacchi KL, Schroeder GM, Asakawa N.
Trost BM, et al. Among authors: sacchi kl.
Org Lett. 2002 Oct 3;4(20):3427-30. doi: 10.1021/ol0265766.
Org Lett. 2002.
PMID: 12323035
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Synthesis and biological evaluation of menthol-based derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1).
Ye B, Bauer S, Buckman BO, Ghannam A, Griedel BD, Khim SK, Lee W, Sacchi KL, Shaw KJ, Liang A, Wu Q, Zhao Z.
Ye B, et al. Among authors: sacchi kl.
Bioorg Med Chem Lett. 2003 Oct 6;13(19):3361-5. doi: 10.1016/s0960-894x(03)00686-3.
Bioorg Med Chem Lett. 2003.
PMID: 12951126
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Structure-activity relationships of substituted benzothiophene-anthranilamide factor Xa inhibitors.
Chou YL, Davey DD, Eagen KA, Griedel BD, Karanjawala R, Phillips GB, Sacchi KL, Shaw KJ, Wu SC, Lentz D, Liang AM, Trinh L, Morrissey MM, Kochanny MJ.
Chou YL, et al. Among authors: sacchi kl.
Bioorg Med Chem Lett. 2003 Feb 10;13(3):507-11. doi: 10.1016/s0960-894x(02)00938-1.
Bioorg Med Chem Lett. 2003.
PMID: 12565961
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