User profiles for E. P. Diamandis

Eleftherios Diamandis

Professor of Laboratory Medicine and Pathobiology, University of Toronto
Verified email at mtsinai.on.ca
Cited by 75577

[HTML][HTML] Cancer immunotherapy: the beginning of the end of cancer?

S Farkona, EP Diamandis, IM Blasutig - BMC medicine, 2016 - Springer
These are exciting times for cancer immunotherapy. After many years of disappointing
results, the tide has finally changed and immunotherapy has become a clinically validated …

Resveratrol: a molecule whose time has come? And gone?

GJ Soleas, EP Diamandis, DM Goldberg - Clinical biochemistry, 1997 - Elsevier
Objectives: Resveratrol (3,5,4′-trihydroxystilbene) is the parent compound of a family of
molecules, including glucosides and polymers, existing in cis and trans configurations in a …

The biotin-(strept) avidin system: principles and applications in biotechnology

EP Diamandis, TK Christopoulos - Clinical chemistry, 1991 - academic.oup.com
The biotin-(strept)avidin system has been used for many years in a variety of different
applications. Here we present a general overview of the system, describe its components and …

The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart …

CR Pace-Asciak, S Hahn, EP Diamandis, G Soleas… - Clinica chimica acta, 1995 - Elsevier
A number of lines of evidence suggest that red wine may be more effective than other
alcoholic beverages in decreasing the risk of coronary heart disease (CHD) mortality. This …

Wine as a biological fluid: history, production, and role in disease prevention

GJ Soleas, EP Diamandis… - Journal of clinical …, 1997 - Wiley Online Library
… But neither this episode nor any of his subsequent drinking adversely affected his longevity,
because in Verse 28 of the same chapter, we are informed: And Noah lived after the flood …

The new human tissue kallikrein gene family: structure, function, and association to disease

GM Yousef, EP Diamandis - Endocrine reviews, 2001 - academic.oup.com
The human tissue kallikrein gene family was, until recently, thought to consist of only three
genes. Two of these human kallikreins, prostate-specific antigen and human glandular …

Strategies for discovering novel cancer biomarkers through utilization of emerging technologies

V Kulasingam, EP Diamandis - Nature clinical practice Oncology, 2008 - nature.com
The introduction of technologies such as mass spectrometry and protein and DNA arrays,
combined with our understanding of the human genome, has enabled simultaneous …

[HTML][HTML] Mass spectrometry as a diagnostic and a cancer biomarker discovery tool: opportunities and potential limitations

EP Diamandis - Molecular & Cellular Proteomics, 2004 - ASBMB
Serum proteomic profiling, by using surfaced-enhanced laser desorption/ionization-time-of-flight
mass spectrometry, is one of the most promising new approaches for cancer diagnostics…

The emerging roles of human tissue kallikreins in cancer

CA Borgoño, EP Diamandis - Nature Reviews Cancer, 2004 - nature.com
Human tissue kallikreins (hKs), which are encoded by the largest contiguous cluster of
protease genes in the human genome, are secreted serine proteases with diverse expression …

Novel therapeutic applications of cardiac glycosides

I Prassas, EP Diamandis - Nature reviews Drug discovery, 2008 - nature.com
Cardiac glycosides are a diverse family of naturally derived compounds that bind to and
inhibit Na + /K + -ATPase. Members of this family have been in clinical use for many years for …