Perineural invasion (PNI) is a prominent characteristic of pancreatic cancer. PNI is a process
whereby cancer cells invade the surrounding nerves, thus providing an alternative route for …

The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium (CPTAC)
investigates tumors from a proteogenomic perspective, creating rich multi-omics datasets …

… information; (f) may include screening measures that are used in conjunction with other
information from the assessment, providing a broader context for interpreting the results; (g) may …

To evaluate the timing of mutations in BRAF (v-raf murine sarcoma viral oncogene homolog
B1) during melanocytic neoplasia, we carried out mutation analysis on microdissected …

… In the immunoprecipitation studies, NIH 3T3 cells were treated with lysis buffer, and lysates
were mixed with anti-Flag antibody and protein G-sepharose. Phosphorylated AKT substrate …

To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors and …

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient
survival. Toward understanding the underlying molecular alterations that drive PDAC …

… Eight out of nine metastases exhibited positive staining (G), which was specific to the
melanoma cells and not to surrounding cell types such as lymphocytes ([H], arrow). Upon …

Although prostate cancer is the most common non-cutaneous malignancy diagnosed in
men in the United States 1, 2, little is known about inherited factors that influence its genetic …

Lung squamous cell carcinoma (LSCC) remains a leading cause of cancer death with few
therapeutic options. We characterized the proteogenomic landscape of LSCC, providing a …