Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

…, K Yamaji, K Takahashi, T Fujioka, R Takata… - Nature …, 2020 - nature.com
The overwhelming majority of participants in current genetic studies are of European ancestry.
To elucidate disease biology in the East Asian population, we conducted a genome-wide …

Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population

R Takata, S Akamatsu, M Kubo, A Takahashi… - Nature …, 2010 - nature.com
… (r 2 ) between the remaining 183 SNPs and selected the 91 SNPs with the lowest P value
within each r … For general statistical analysis, we used R statistical environment version 2.6.1 or …

Endoscopic submucosal dissection for early gastric cancer: results and degrees of technical difficulty as well as success

…, J Kato, H Kawamoto, S Fujiki, R Takata… - …, 2006 - thieme-connect.com
Results: The rate of curative en bloc resection was 84%(93% of the lesions overall were
resected in one piece), with a perforation rate of 6.1%(all perforations were managed …

Association of a novel long non‐coding RNA in 8q24 with prostate cancer susceptibility

…, L Piao, K Ashikawa, N Hosono, R Takata… - Cancer …, 2011 - Wiley Online Library
… the pairwise tagging method with the following criteria: r 2 > 0.9, minor allele frequency >5% …
(B) Pair-wise linkage disequilibrium map as measured by r 2 using SNP with MAF ≥0.05. …

Present status and future perspective of peptide‐based vaccine therapy for urological cancer

…, T Katagiri, R Kato, Y Kato, R Takata - Cancer …, 2018 - Wiley Online Library
Use of peptide‐based vaccines as therapeutics aims to elicit immune responses through
antigenic epitopes derived from tumor antigens. Peptide‐based vaccines are easily …

Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and …

…, M Iiizumi, Y Anazawa, T Tsunoda, R Takata… - Cancer research, 2004 - AACR
To characterize the molecular feature in prostate carcinogenesis and the putative transition
from prostatic intraepithelial neoplasia (PIN) to invasive prostate cancer (PC), we analyzed …

Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression …

R Takata, T Katagiri, M Kanehira, T Tsunoda… - Clinical cancer …, 2005 - AACR
… Mean (μ) and standard deviation (σ) were calculated from the log-transformed relative
expression ratios of each gene in responder (r) and nonresponder (n) cases. A discrimination …

Molecular features of hormone-refractory prostate cancer cells by genome-wide gene expression profiles

K Tamura, M Furihata, T Tsunoda, S Ashida, R Takata… - Cancer research, 2007 - AACR
One of the most critical issues in prostate cancer clinic is emerging hormone-refractory
prostate cancers (HRPCs) and their management. Prostate cancer is usually androgen …

[PDF][PDF] Missense mutations in the copper transporter gene ATP7A cause X-linked distal hereditary motor neuropathy

…, J Tang, RM Llanos, S Chu, RI Takata… - The American Journal of …, 2010 - cell.com
Distal hereditary motor neuropathies comprise a clinically and genetically heterogeneous
group of disorders. We recently mapped an X-linked form of this condition to chromosome …

Elevated serum myostatin level is associated with worse survival in patients with liver cirrhosis

…, N Ikeda, T Takashima, R Takata… - Journal of cachexia …, 2017 - Wiley Online Library
Background We aimed to elucidate the relationship between serum myostatin levels and
other markers including skeletal muscle mass and to investigate the influence of serum …