Macroautophagy (hereafter called autophagy) is a highly conserved physiological process
that degrades over-abundant or damaged organelles, large protein aggregates and invading …

Sirtuin 3 (SIRT3) is one of the most prominent deacetylases that can regulate acetylation
levels in mitochondria, which are essential for eukaryotic life and inextricably linked to the …

Cardiolipin (CL) is a unique dimeric phospholipid that exists almost exclusively in the inner
mitochondrial membrane (IMM) in eukaryotic cells. Two chiral carbons and four fatty acyl …

Ferroptosis, triggered by discoordination of iron, thiols and lipids, leads to the accumulation
of 15-hydroperoxy (Hp)-arachidonoyl-phosphatidylethanolamine (15-HpETE-PE), generated …

During cancer therapy, phagocytic clearance of dead cells plays a vital role in immune
homeostasis. The nonapoptotic form of cell death, ferroptosis, exhibits extraordinary potential in …

Myocardial ischemia/reperfusion (I/R) injury is a classic type of cardiovascular disease
characterized by injury to cardiomyocytes leading to various forms of cell death. It is believed that …

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the gradual loss
of midbrain dopaminergic neurons in association with aggregation of α-synuclein. Oxidative …

Nine new phenylpropanoids, one new coumarin, and 43 known polyphenols were isolated
from wolfberry. Their structures were determined by spectroscopic analyses, chemical …

Halloysite nanotubes (HNTs) are natural aluminosilicates with unique hollow lumen structure,
also having high specific area, good biocompatibility, nontoxicity, and low price. Here, we …

Halloysite nanotubes (HNTs), a traditional mineral Chinese medicine, have been used to stop
bleeding for thousands of years. However, the coagulation mechanisms of HNTs and their …