Radiomics is an emerging translational field of research aiming to extract mineable high-dimensional
data from clinical images. The radiomic process can be divided into distinct steps …

Despite major improvements in outcome over the past decades, acute myeloid leukemia (AML)
remains a life-threatening malignancy in children, with current survival rates of ∼ 70%. …

Acute pancreatitis, chronic pancreatitis and pancreatic cancer are responsible for most of
the burden of exocrine pancreatic disease. Glandular damage from recurrent bouts of acute …

Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy
of unknown genetic basis. We performed whole-genome sequencing of 12 ETP ALL cases …

… demonstrate that expression profiling can not only accurately identify the known prognostically
important leukemia subtypes, but can further enhance our ability to assess a patient’s risk …

Background Prophylactic cranial irradiation has been a standard treatment in children with
acute lymphoblastic leukemia (ALL) who are at high risk for central nervous system (CNS) …

Human T cell leukemias can arise from oncogenes activated by specific chromosomal
translocations involving the T cell receptor genes. Here we show that five different T cell …

Background Children with Philadelphia chromosome–positive acute lymphoblastic leukemia
(Ph-positive ALL) have a poor prognosis, and there is no consensus on the optimal …

Context Colorectal cancer is the third most common form of cancer and the fourth most
frequent cause of cancer deaths worldwide. The association between cigarette smoking and …

We have developed a restriction map of the chromosome 21 breakpoint region involved in t(8;21)(q22;q22.3)
acute myelogenous leukemia (AML) and have isolated a genomic junction …