Multitarget therapy for induction treatment of lupus nephritis: a randomized trial

…, P Fu, Z Ni, J Chen, H Lin, F Liu, Y He, Y He… - Annals of internal …, 2015 - acpjournals.org
Background: Treatment of lupus nephritis (LN) remains challenging. Objective: To assess the
efficacy and safety of a multitarget therapy consisting of tacrolimus, mycophenolate mofetil, …

Urinary neutrophil gelatinase-associated lipocalin (NGAL) is an early biomarker for renal tubulointerstitial injury in IgA nephropathy

H Ding, Y He, K Li, J Yang, X Li, R Lu, W Gao - Clinical Immunology, 2007 - Elsevier
Renal tubulointerstitial injury plays an important role in the development of IgA nephropathy
(IgAN), the most common form of glomerulonephritis. Few currently in use biomarkers can …

[HTML][HTML] Optineurin-mediated mitophagy protects renal tubular epithelial cells against accelerated senescence in diabetic nephropathy

…, L Lin, W Zhang, L Wang, J Zhang, K Li, Y He - Cell death & …, 2018 - nature.com
Premature senescence is a key process in the progression of diabetic nephropathy (DN).
Premature senescence of renal tubular epithelial cells (RTEC) in DN may result from the …

CircCDK8 regulates osteogenic differentiation and apoptosis of PDLSCs by inducing ER stress/autophagy during hypoxia

J Zheng, X Zhu, Y He, S Hou, T Liu… - Annals of the New …, 2021 - Wiley Online Library
Mounting evidence indicates that circular RNAs (circRNAs) have essential roles in several
diseases, including periodontitis. Periodontal ligament stem cells (PDLSCs) exhibit potential …

[HTML][HTML] Estrogen deficiency aggravates apical periodontitis by regulating NLRP3/caspase-1/IL-1β axis

X Guan, Y Guan, C Shi, X Zhu, Y He, Z Wei… - American journal of …, 2020 - ncbi.nlm.nih.gov
Estrogen plays critical roles in apical periodontitis and subsequent bone loss, however the
mechanism is not clear yet. In this study, we aimed to study the underlying mechanism of …

ATP-P2X4 signaling mediates NLRP3 inflammasome activation: a novel pathway of diabetic nephropathy

…, J Zhang, W Zhang, J Zhang, J Yang, K Li, Y He - The international journal …, 2013 - Elsevier
Tubulointerstitial inflammation plays a key role in the development of diabetic nephropathy (DN).
Cytokines in the IL-1 family are the key pro-inflammatory cytokines of tubulointerstitial …

MiR-34 modulates Caenorhabditis elegans lifespan via repressing the autophagy gene atg9

J Yang, D Chen, Y He, A Meléndez, Z Feng, Q Hong… - Age, 2013 - Springer
Evidence for a regulatory role of the miR-34 family in senescence is growing. However, the
exact role of miR-34 in aging in vivo remains unclear. Here, we report that a mir-34 loss-of-…

Diagnostic value of serum procalcitonin for acute pyelonephritis in infants and children with urinary tract infections: an updated meta-analysis

H Zhang, J Yang, L Lin, B Huo, H Dai, Y He - World journal of urology, 2016 - Springer
Purpose The aims were to assess (1) the diagnostic value of serum procalcitonin (PCT) for
acute pyelonephritis (APN) in infants and children with urinary tract infections (UTIs) and (2) …

Delivering PD-1 inhibitory signal concomitant with blocking ICOS co-stimulation suppresses lupus-like syndrome in autoimmune BXSB mice

H Ding, X Wu, J Wu, H Yagita, Y He, J Zhang, J Ren… - Clinical …, 2006 - Elsevier
BXSB mice spontaneously develop an autoimmune syndrome characterized by
hypergammaglobulinemia, autoantibody production, and the development of fatal glomerulonephritis …

[HTML][HTML] Diagnostic accuracy of PLA2R autoantibodies and glomerular staining for the differentiation of idiopathic and secondary membranous nephropathy: an …

H Dai, H Zhang, Y He - Scientific reports, 2015 - nature.com
The diagnostic performance of M-type phospholipase A2 receptor (PLA2R) autoantibodies
and PLA2R glomerular staining in discriminating between idiopathic membranous …